Friday, September 30, 2011

Glycosylation!

You might be asking yourself, what exactly is glycosylation? Glycosylation is the adding of a glycoside (sugar) to a protein. This process occurs in the endoplasmic reticulum (ER), while the polypeptide is still being biosynthesized and is partially unfolded. This suggests that glycosylation plays a role in protein folding and stability. Glycosylation is one of the most common and important protein modifications.


(The image above shows O-linked glycosylation)

This article basically talks about the process of glycosylation and its glycoproteins. A glycoprotein is formed when a membrane associated carbohydrate is exclusively in the form of oliogsaccharides covalently attached to proteins. Glycoproteins consist of proteins covalently linked to a carbohydrate.

(The image above shows N-linked glycosylation)

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